SpinPro Reactor

SpinPro Reactor

SpinPro technology is well suited for multiphase chemistry:

  • Liquid/gas
  • Liquid/liquid
  • Precipitation reactions
  • Controlled emulsification.

Key Features are:

  • Excellent mass transfer
  • Excellent heat transfer
  • Closed system
  • Economic and safe operation due to low reactor volume
  • Scalability to tonne-scale production
  • Modular set up enabling custom configurations

The SpinPro Reactor

Investment Costs

With SpinPro technology more efficient and safer process conditions are met,  investments (CAPEX) can be reduced significantly. Often quality is improved, the yield increased with less byproduct formation and the final product properties improved. Typically CAPEX reductions of 20-70% can be realised depending on the process. Main drivers are the lower costs of safety measurements and work up installations.

Operational Costs

In most applications a significant decrease in operational costs (OPEX), due to the higher efficiencies and less workup of the product, even to the extent that processes could be performed undiluted, saving tremendously on workup.

Ease of Operation

Further advantages are easy shut down, cleaning and start-up. A major benefit is the flexibility to make different products in the same installation due to fast turnaround. The SpinPro can be stopped, cleaned and restarted within a few hours.

The SpinPro Reactor is not to be confused with a ‘thin film spinning disc reactor‘. Read about the differences in this blog post.

Application Examples

  • Organometallic Chemistry

    Read more about the benefits of butyl-lithium chemistry performed in SpinPro reactors.

  • Nitration

    Easy to scale up and safe. Flexible skid for production operational.

  • Halogenation

    Chlorination, gas / liquid reaction using Tantalum SpinPro reactor.

  • Controlled Emulsification

    Read more about precise and accurate emulsification in the SpinPro in this post.

SpinPro Reactor Specifications

The table below illustrates the SpinPro Reactor configurations. A range of options is available; higher pressures, higher temperatures, ATEX and GMP. Several setups, complete with dosing systems, are available for rent. Flowid offers process development support to assist you with continuous processing. For more information contact Flowid
SpinPro R10  SpinPro R300
Volume [ml] 19 135/230*
Stages [#] 3 3
Disc speed [RPM] 8000 3000
Max Pressure [Barg] 10 10
Max Temperature [C] 160 160
Download leaflet R10 Leaflet R300 Leaflet

*Volume is dependent on disc type and customer needs

Examples relevant to the SpinPro Reactor:

Butyl-Lithium Chemistry in the Flowid SpinPro Reactors

Flowid has performed experiments to improve the efficiency and safety of highly hazardous lithium-halogen exchange reactions. These experiments show the advantages of using the SpinPro technology versus conventional batch technology for these kinds of reactions. [...]

Precise and Accurate Emulsification in the SpinPro

The SpinPro is unique in the field of emulsification as it allows for a high degree of freedom on the amount of shear that is applied to the emulsifying fluids, independent of the total throughput [...]

Making the impossible possible: Butyl Lithium chemistry

The companies ChemConnection B.V., Ajinomoto Omnichem N.V. and Flowid B.V., in cooperation with ISPT, started a combined project, partially funded by the Netherlands Enterprise Agency (RVO), to investigate the potential of performing organic synthesis with [...]

SpinPro R300 eliminates necessity of Hydrogen Sulphide in Multiphase reaction

The SpinPro reactor has recently been used on-site. Goal of this project was to experimentally determine the performance of the SpinPro reactor for a multiphase reaction between a gas and two liquid phases, one aqueous [...]

Whitepaper: Successful Scale Up of Butyl-Lithium using the SpinPro Reactor

In a pursuit of improving safety and process efficiency, Biogen a top Biotech company collaborated with Proteaf Technologies and Flowid to scale up a highly hazardous lithium-halogen exchange followed by quench reaction sequence at ChemConnection, [...]

SpinPro Reactor for Butyl Lithium Reaction

Flowid demonstrated that the SpinPro Reactor is well suited for performing hazardous and pyrophoric Lithium Halogen Exchange. An extensive engineering and safety effort resulted in successful experiments. Lithium Halogen Exchange is a type of carbon-carbon [...]