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Precise and Accurate Emulsification in the SpinPro

The SpinPro is unique in the field of emulsification as it allows for a high degree of freedom on the amount of shear that is applied to the emulsifying fluids, independent of the total throughput through the system. This results in constant droplet size distribution at the outlet with a high degree of control. Recently, [...]

Making the impossible possible: Butyl Lithium chemistry

The companies ChemConnection B.V., Ajinomoto Omnichem N.V. and Flowid B.V., in cooperation with ISPT, started a combined project, partially funded by the Netherlands Enterprise Agency (RVO), to investigate the potential of performing organic synthesis with butyl lithium as reagent in a SpinPro Reactor. Motivation of the project was to proof the outstanding performance of the [...]

By |april 1st, 2016|chemistry, pharma, spinpro reactor, SpinProReactor|0 Comments

Whitepaper: Successful Scale Up of Butyl-Lithium using the SpinPro Reactor

In a pursuit of improving safety and process efficiency, Biogen a top Biotech company collaborated with Proteaf Technologies and Flowid to scale up a highly hazardous lithium-halogen exchange followed by quench reaction sequence at ChemConnection, Oss, NL. The sequence demonstrated successful scale up of laboratory spinning disk technology to the SpinPro-- a production scale spinning [...]

SpinPro Reactor for Butyl Lithium Reaction

Flowid demonstrated that the SpinPro Reactor is well suited for performing hazardous and pyrophoric Lithium Halogen Exchange. An extensive engineering and safety effort resulted in successful experiments. Lithium Halogen Exchange is a type of carbon-carbon bond forming reaction frequently performed in lab scale organic synthesis. Although the reaction is performed at scale, producing pharmaceuticals, pesticides, [...]

Heterogeneous Catalysis in the SpinPro Reactor

Heterogeneous catalysis is of paramount importance in chemical industry, but it often involves incorporating difficult and mass transfer limited unit operations. The SpinPro Reactor has proven itself to drastically increase solid-liquid mass transfer rates, while simultaneously tackling the problems involved in downstream solids handling. The SpinPro consists of three rotor-stator stages in series. Each compartment [...]

By |februari 17th, 2015|biobased, chemistry, mixing, pharma, reaction, spinpro reactor, SpinProReactor|0 Comments

SpinPro Reactor suited for Butyl Lithium reaction

Flowid demonstrated that the SpinPro Reactor is well suited for performing hazardous and pyrophoric Lithium Halogen Exchange. An extensive engineering and safety effort resulted in successful experiments performed in Flowid’s own facilities in Eindhoven, The Netherlands. Lithium Halogen Exchange is a type of carbon-carbon bond forming reaction frequently performed in lab scale organic synthesis. Although [...]

Launch of EmulTech’s Infinity, engineered and realised by Flowid

Eindhoven University of Technology spin-off EmulTech last week launched INFINITY: a unit that allows pharmaceutical companies to encapsulate medicines with very high precision. The resulting microparticle all have exactly the same size and medicine content, allowing extremely precise control of delivery. This is very important in applications such as asthma respirators. Encapsulating medicines is currently [...]

By |augustus 28th, 2014|case, dosing systems, flowflex, pharma|0 Comments

Flowid Pilot Plant Capabilities

In eleven weeks Flowid engineered and constructed a pharmaceutical pilot plant. This plant is in operation since the beginning of 2014 in Flowid’s pilot hall. We look forward to discuss our pilot plant capabilities with you. A static mixer forms the hart of the pilot plant. Flowid is specialised in continues processing based on technologies [...]

By |juni 2nd, 2014|market, mixing, pharma, ProcesEngineering, StaticMixer|0 Comments

Case study – Flexibility

Problem Description One of our customers, a large manufacturer of flow reactors in the (pharma) industry, was looking for a suitable testing site to further develop a highly exothermic process using dangerous chemicals. They had had success in small scale research and wanted to optimize and scale up the process. However, after having requested access [...]

By |maart 10th, 2014|case, flexible, flowflex, market, micro reactor, pharma, reaction|0 Comments

Flowid and EmulTech realize unique platform for emulsification processes

The Eindhoven high-tech companies Flowid B.V. and EmulTech B.V. cooperated in the realization of a unique laboratorial platform for EmulTech’s ET4ME technology. This patented microfluidic technology is used for the development of drug delivery formulations with high degree of uniformity, solubility, tailored release, benign processes and reproducibility. Flowid succeeded in the design and realization of [...]

By |juli 4th, 2012|dosing systems, mixing, pharma|0 Comments