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So far Flowid has created 18 blog entries.

SpinPro R10 – Flow reactor, for chemical process development and production

SpinPro R10 is our small-scale ceramic (SiC) flow reactor, suited for chemical process development and production. SpinPro R10 enables processes to be developed and directly scaled to tonne-scale production using SpinPro R300. Made from silicon carbide, SpinPro offers the superior chemical resistance and heat transfer needed for challenging flow chemistry applications. Excellent mass transfer Excellent [...]

By |september 9th, 2017|uncategorized|0 Comments

Butyl-Lithium Chemistry in the Flowid SpinPro Reactors

Flowid has performed experiments to improve the efficiency and safety of highly hazardous lithium-halogen exchange reactions. These experiments show the advantages of using the SpinPro technology versus conventional batch technology for these kinds of reactions. Key results are the ease of scaling up to commercial production and flexibility to perform different chemical reactions in the [...]

Buchem Experiences the Advantages of Flow Chemistry

Chemtrix, Flowid & Buchem are proud to announce their collaboration on a joint project in the area of flow chemistry. Buchem specializes in the development, manufacture & worldwide sales of chemicals for the laboratory, hospital & chemical markets, with a main focus on production scales up to 1000 kg per year. In 2015, Buchem encountered [...]

By |juni 1st, 2017|dosing systems, uncategorized|0 Comments

Precise and Accurate Emulsification in the SpinPro

The SpinPro is unique in the field of emulsification as it allows for a high degree of freedom on the amount of shear that is applied to the emulsifying fluids, independent of the total throughput through the system. This results in constant droplet size distribution at the outlet with a high degree of control. Recently, [...]

Making the impossible possible: Butyl Lithium chemistry

The companies ChemConnection B.V., Ajinomoto Omnichem N.V. and Flowid B.V., in cooperation with ISPT, started a combined project, partially funded by the Netherlands Enterprise Agency (RVO), to investigate the potential of performing organic synthesis with butyl lithium as reagent in a SpinPro Reactor. Motivation of the project was to proof the outstanding performance of the [...]

By |april 1st, 2016|chemistry, pharma, spinpro reactor, SpinProReactor|0 Comments

The SpinPro R300; not your everyday Spinning Disc Reactor

The SpinPro reactor is based on patented rotor-stator spinning disc technology. Traditionally, two types of spinning disc reactors are known in chemical industry. The first, the thin film spinning disc reactor consists of a rotating disk in a large collection tank. Liquid is fed on top of the disc near the axis of rotation and flows [...]

By |februari 24th, 2016|Blog, NoNews, SpinProReactor|0 Comments

Chimex Dosing Skid

Chimex is a French company that designs, develops, and markets increasingly eco-friendly processes for the fine chemical, biotech, and cosmetic industries. Flowid has recently engineered and realised the construction of a dosing skid for Chimex. The skid complies with ATEX regulations and is constructed completely using highly chemically resistant materials. The configuration comprises two high-end [...]

By |februari 23rd, 2016|chemistry, dosing systems, micro reactor, ProcesEngineering, reaction|0 Comments

Whitepaper: Successful Scale Up of Butyl-Lithium using the SpinPro Reactor

In a pursuit of improving safety and process efficiency, Biogen a top Biotech company collaborated with Proteaf Technologies and Flowid to scale up a highly hazardous lithium-halogen exchange followed by quench reaction sequence at ChemConnection, Oss, NL. The sequence demonstrated successful scale up of laboratory spinning disk technology to the SpinPro-- a production scale spinning [...]

SpinPro Reactor for Butyl Lithium Reaction

Flowid demonstrated that the SpinPro Reactor is well suited for performing hazardous and pyrophoric Lithium Halogen Exchange. An extensive engineering and safety effort resulted in successful experiments. Lithium Halogen Exchange is a type of carbon-carbon bond forming reaction frequently performed in lab scale organic synthesis. Although the reaction is performed at scale, producing pharmaceuticals, pesticides, [...]

SpinPro Reactor suited for Butyl Lithium reaction

Flowid demonstrated that the SpinPro Reactor is well suited for performing hazardous and pyrophoric Lithium Halogen Exchange. An extensive engineering and safety effort resulted in successful experiments performed in Flowid’s own facilities in Eindhoven, The Netherlands. Lithium Halogen Exchange is a type of carbon-carbon bond forming reaction frequently performed in lab scale organic synthesis. Although [...]